The hyperpolarization-activated cyclic nucleotide-gated cationic (HCN) channels comprise four members termed HCN1–4
The hyperpolarization-activated cyclic nucleotide-gated cationic (HCN) channels comprise four members termed HCN1–4 ; they have a pacemaker activity in excitable tissues controlling excitability, establishment of the resting membrane potential, dendritic integration, synaptic transmission and action potential firing.
ICE has established stable expression cell lines such as HCN1, HCN2, HCN4, etc., in dedication to provide appropriate drug screening services.
HCN1 Assay Data Sheet
HCN1（hyperpolarization activated cyclic nucleotide
gated potassium channel 1）
whole cell patch clamp
Pace maker current of the mammalian heart, bradycardia,
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